We occasionally receive requests from Customers regarding the management of .DS_Store files. The primary reason for this is that by default, OS X clients do not request these files have the hidden attribute set, since on OS X the default setting is that files that begin with a . (dot) are not visible when browsing.
However, this is not the case on Windows, so Windows clients accessing the same directories on the server will see the .DS_Store files when browsing. You can read about what these files do at http://en.wikipedia.org/wiki/.DS_Store
If one were to use the Windows Server File Server Resource Manager File Screening feature to block the creation of .DS_Store files, copies of folders containing a .DS_Store file would fail.
The reason for this is when an OS X client starts to copy a folder that contains a .DS_Store file, the .DS_Store file is usually the first file that the Finder will try to copy and when that file copy is blocked and that failure returned to the OS X client, the Finder will halt the copy job.
Apple has published a knowledge base article about how to configure an OS X client to not request the creation of .DS_Store file on a network share. This article is at
Mac OS X v10.4 and later: How to prevent .DS_Store file creation over network connections
This article is marked "Archived", but in this case, it still applies.