You can clone basic disks from your operating system or from Acronis Bootable Media
Using Acronis Disk Director 12 you can clone only basic MBR disks. GPT disks cannot be cloned.
You cannot clone a single partition, only cloning of an entire disk is possible.
Source disk volumes can be cloned to the target disk "as is" or resized proportionally.
It is recommended not to format the source hard disk after cloning until you are sure that the cloned target disk boots fine.
(!) Only basic disks can be cloned with Acronis Disk Director 12:
Cloning dynamic disks is not supported:
(!) When cloning a basic disk, you have an option to copy disk NT signature. If you copy NT signature, you need to unplug one of the disks from the machine after cloning and before the first startup.
See also Cloning Laptop Hard Disk.